In adults with established coeliac disease, exocrine pancreatic insufficiency (EPI) may develop as a co-existing condition. When EPI is confirmed, management extends beyond the standard dietary approach and a targeted intervention is indicated.
Confirmed exocrine pancreatic insufficiency in a patient with coeliac disease. In adult patients with CeD, pancreatic enzyme replacement therapy may be indicated once exocrine pancreatic insufficiency is confirmed.
In this setting, a specific form of enzyme replacement therapy is part of the recommended management, used alongside dietary treatment. The complete structured regimen — including all components and their application — is available in the full protocol below.
Relief of steatorrhoea and bloating, enhanced nutrient absorption, and improved quality of life.
DOI: 10.1002/ueg2.70195
In adult patients with CeD, pancreatic enzyme replacement therapy (PERT) may be indicated when exocrine pancreatic insufficiency is confirmed.
PERT can improve digestive function, relieve symptoms such as steatorrhoea and bloating, enhance nutrient absorption, and improve QoL.
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