Acute Digoxin Toxicity from Bolus Ingestion in Adults: Treatment Approach

A single acute bolus ingestion of digoxin without antecedent background use, in an adult patient. This is pharmacokinetically distinct from chronic accumulation toxicity, and the absence of prior drug loading opens a specific management window relevant to elimination.

Management in this setting includes a gastrointestinal decontamination strategy directed at the elimination kinetics of digoxin following acute ingestion. The complete protocol — including which interventions apply, how patient age informs selection, and the full decision sequence — is available via the link below.