Treatment of Carcinoid Syndrome with Diarrhoea, Dementia, and Sun-Sensitive Dermatitis
This protocol covers Carcinoid syndrome in patients presenting with diarrhoea and dementia alongside sun-sensitive dermatitis and measurably low plasma vitamin B3 (niacin) levels — a specific clinical sub-population requiring targeted management.
Clinical Scenario
The combination of diarrhoea, dementia, and sun-sensitive dermatitis in the context of Carcinoid syndrome is accompanied by low circulating vitamin B3 (niacin) levels. These concurrent findings define the target population for this protocol and directly inform its therapeutic focus.
Therapeutic Approach
Treatment involves oral vitamin B3 supplementation, with the specific agent selection and any further adjustments guided by circulating niacin levels — full protocol details are available via the link below …
Treatment goal: Normalisation of circulating vitamin B3 (niacin) levels.
References
- Sun-sensitive dermatitis, diarrhoea, dementia
- Plasma vitamin B3 levels
- Patients with niacin deficiency or pellagra should be started on niacin or nicotinamide 200–250 mg PO once daily with further treatment tailored to circulating levels.
DOI: 10.1111/jne.13146
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