Recurrent buccal mucosa cancer presents a challenging clinical scenario, particularly when re-resection is not an option and the patient's performance status is limited. Management in this setting requires a carefully individualized approach.
This protocol addresses recurrent buccal mucosa cancer in patients for whom surgery is not feasible. The approach depends on prior treatment history — specifically, whether the patient has previously received radiotherapy — and on overall performance status, which guides the intensity of intervention.
For operable recurrences in radiotherapy-naïve patients, surgery followed by post-operative radiotherapy, with or without chemotherapy, or radical radiotherapy for selected early-stage recurrences, may be considered.
When surgery is not feasible and performance status is poor, treatment is individualized. The approach involves a palliative modality — the specific choice depends on prior radiotherapy exposure — combined with best supportive care.
DOI: 10.4103/0971-5851.138953
For recurrent disease, if recurrence is operable and patient is RT naïve, surgery followed by PORT with or without chemotherapy or radical RT (for recurrent T1/T2) may be employed.
If surgery is not feasible and patient has poor performance status the treatment should be individualized.
If RT naïve, palliative RT else palliative chemotherapy may be employed along with best supportive care.
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