Treatment of Brugada Syndrome with Type 1 Brugada ECG Pattern and Arrhythmic Syncope

This protocol addresses patients with Brugada syndrome who have a type 1 Brugada ECG pattern together with a history of arrhythmic syncope.

Clinical Scenario

The patient presents with a confirmed type 1 Brugada ECG pattern and has experienced arrhythmic syncope.

Treatment Approach

The protocol involves a catheter-based interventional strategy. Which specific arrhythmic sources are targeted, and the complete clinical algorithm, are detailed in the full regimen.

Clinical Goals

Suppression of recurrent ventricular fibrillation Normalization of the electrocardiogram

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References

DOI: 10.1093/eurheartj/ehac262

ICD implantation should be considered in patients with type 1 Brugada pattern and an arrhythmic syncope.

Catheter ablation of triggering PVCs and/or RVOT epicardial substrate should be considered in BrS patients with recurrent appropriate ICD shocks refractory to drug therapy.

Ablation of these abnormal areas can markedly suppress recurrent VF and normalize the ECG in .75% of patients.

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