Brugada syndrome
ICD-10 I49.8 · ICD-11 BC65.1

Brugada Syndrome in Survivors of Aborted Cardiac Arrest or with Documented Spontaneous Sustained Ventricular Tachycardia

Clinical Scenario

This protocol applies to patients with Brugada syndrome who have survived an aborted cardiac arrest or who have documented spontaneous sustained ventricular tachycardia — a high-risk subgroup for whom structured, evidence-based management is essential.

ICD implantation is recommended in patients with Brugada syndrome who are survivors of an aborted cardiac arrest and/or have documented spontaneous sustained ventricular tachycardia.

Treatment Approach

In addition to device-based therapy, a catheter ablation procedure targeting specific areas of abnormal ventricular substrate may play a role in management — particularly in cases of recurrent arrhythmia. The full sequence, indication criteria, and technical approach are detailed in the complete protocol.

Clinical goals: Suppression of recurrent ventricular fibrillation and normalization of the electrocardiogram.
Instant Access to Structured Evidence-Based Regimens

References

  • ICD implantation is recommended in patients with BrS who: (a) Are survivors of an aborted CA and/or (b) Have documented spontaneous sustained VT.
  • Catheter ablation of triggering PVCs and/or RVOT epicardial substrate should be considered in BrS patients with recurrent appropriate ICD shocks refractory to drug therapy.
  • Ablation of these abnormal areas can markedly suppress recurrent VF and normalize the ECG in >75% of patients.

DOI: 10.1093/eurheartj/ehac262

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