Treatment of Brown-Séquard Syndrome in Adults (≥14 Years) with Acute Spinal Cord Injury Presenting Within 8 Hours

Clinical scenario

This protocol is for adult patients aged 14 years or older who present with acute spinal cord injury within 8 hours of injury onset. The presentation window is a defining factor in the management approach.

Patient population

Applicable across postresuscitation injury severity grades (ASIA A to D), covering both the acute phase and early rehabilitation. Age — specifically adult status at 14 years or older — is a primary eligibility criterion for this protocol.

Critical window: The 8-hour mark from injury onset determines eligibility for time-sensitive components of this management approach.

Approach

Management combines early surgical intervention with time-critical pharmacological measures; specific eligibility criteria, sequencing, and the full regimen are available in the complete protocol.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1177/2192568217703387

This guideline is to be applied in both the acute and rehabilitation phases of acute SCI in adult (14 years old) patients with postresuscitation American Spinal Injury Association (ASIA) grades A to D.

We suggest that early surgery be offered as an option for adult acute SCI patients regardless of level.

We suggest that anticoagulant thromboprophylaxis be offered routinely to reduce the risk of thromboembolic events in the acute period after SCI.

We suggest that anticoagulant thromboprophylaxis, consisting of either subcutaneous low-molecular weight heparin or

We suggest a 24-hour infusion of high-dose MPSS be offered to adult patients within 8 hours of acute SCI as a treatment option.

View source ↗