Treatment of Bone Metastases with Pathologic Fracture
Pathologic fractures are a serious complication of bone metastases, occurring when skeletal
involvement compromises structural integrity. Both complete fractures and impending fractures
require prompt, durable management tailored to the patient's overall clinical situation.
Clinical scenario
Bone metastases presenting with pathologic fracture — or an impending fracture at significant
risk of completion. The management approach must account for expected survival when selecting
between fixation and reconstruction strategies.
Treatment approach (partial)
The protocol involves surgical intervention — fixation or reconstruction depending on clinical
context — combined with postoperative radiation to the affected site.
The complete sequencing, patient selection criteria, and radiation
parameters are detailed in the full protocol…
References
DOI: 10.1007/s12094-016-1590-1
- Complete and impending pathologic fractures should be treated with durable fixation or reconstruction depending on the patient's expected survival.
- Radiotherapy is indicated for most patients after fixation of a complete or impending pathologic fracture of any bone.
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