In bicuspid aortic valve, the pattern of aortic involvement matters. When root phenotype bicuspid aortopathy is present alongside a maximum aortic diameter reaching 50 mm or above, a specific intervention threshold is crossed and management follows a defined pathway.
Root phenotype bicuspid aortopathy is identified when the sinus diameter exceeds the tubular diameter — distinguishing it from tubular phenotype disease. The critical diameter threshold triggering the recommended approach in this phenotype is a maximum aortic diameter of ≥50 mm.
Management in this scenario involves a surgical intervention directed at the aortopathy. The complete protocol — including the specific procedural approach, patient-level considerations, and decision criteria — is available in the full regimen.
DOI: 10.1093/eurheartj/ehae179