Benign liver tumor
ICD-10 D13.4 · ICD-11 2E92.7

Treatment of Benign Liver Tumor with Multiple Hepatocellular Adenomas

Patients with multiple hepatocellular adenomas represent a distinct and clinically challenging subset of benign liver tumor. Management decisions in this setting depend on careful assessment of tumour characteristics and the patient's overall hepatic status.

Clinical Scenario

This protocol applies to benign liver tumor presenting as multiple hepatocellular adenomas. Management should be guided by the size of the largest tumour, together with an evaluation of total lesion burden and any underlying liver disease.

Treatment Approach — Partial Overview

In certain patients with multiple hepatocellular adenomas, a major surgical intervention involving the liver may be considered — but only when specific clinical conditions are present. The complete eligibility criteria, evidence grading, and full management algorithm are available in the structured protocol.

Instant Access to Structured Evidence-Based Regimens

References

  1. The management of patients with multiple HCA should be based on the size of the largest tumour (evidence level III, grade of recommendation 2)
  2. Because it often is impossible to resect all tumours in patients with multiple HCAs, liver transplantation has been proposed, but should only be considered in patients with more than 10 lesions and underlying liver disease.
  3. Liver transplantation is not recommended in multiple HCA, but might be considered in individuals with underlying liver disease (evidence level III, grade of recommendation 2)
DOI: 10.1016/j.jhep.2016.04.001 View source ↗