Papillary fibroelastoma (PFE) is a benign cardiac tumor that carries meaningful embolic risk depending on its anatomical location and size. This protocol addresses the specific subset of patients whose PFE is situated on the left side of the heart or whose tumor measures more than 10 mm in diameter.
Left-sided location or larger tumor size significantly elevates the risk of thromboembolic complications, including stroke. These features define a high-priority subgroup in which active intervention is warranted rather than watchful waiting.
DOI: 10.1007/s12032-025-02661-0
For left-sided PFEs or larger than 10 mm, surgical removal is recommended due to the increased risk of stroke.
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