Treatment of Benign Heart Tumor in Cardiac Rhabdomyoma

Cardiac rhabdomyoma is a specific presentation of benign heart tumor that occurs predominantly in the pediatric population. This protocol addresses its clinical management, including considerations for patients whose anatomy or associated conditions may limit conventional surgical approaches.

Clinical Scenario

Cardiac rhabdomyoma represents the most common primary cardiac tumor in children, accounting for 50–60% of pediatric primary cardiac tumors. Its management requires careful evaluation of tumor characteristics, symptom burden, and associated systemic conditions.

Treatment Approach

When surgical resection is not feasible, a targeted medical approach may be considered in selected patients — particularly those with an associated systemic condition. The full regimen, eligibility criteria, and sequencing are detailed in the structured protocol.

→ Complete algorithm and criteria available via the link below.

Instant Access to Structured Evidence-Based Regimens

References

Rhabdomyomas are the most common tumors in pediatric PCTs, comprising 50–60% of cases.

In cases where surgical resection is not feasible despite the presence of symptoms, treatment with mTOR inhibitors may be considered, particularly in patients with tuberous sclerosis complex.

DOI: 10.1007/s12032-025-02661-0

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