Treatment of Benign Adrenal Tumor: Unilateral Adrenal Mass with Radiological Findings Suspicious of Malignancy and Signs of Local Invasion

A unilateral adrenal mass that carries both radiological features suspicious for malignancy and imaging evidence of local invasion represents a distinct and high-stakes clinical scenario. The operative strategy in this setting is guided by specific recommendations that differ from those applied to lower-risk adrenal masses.

Clinical Scenario

Unilateral adrenal mass with radiological findings suspicious of malignancy and signs of local invasion. This imaging profile carries direct implications for the choice and conduct of surgery.

Treatment Approach

Evidence supports an open surgical approach carried out by a specifically qualified, high-experience specialist. The complete operative protocol — including surgical planning, decision criteria, and specialist requirements — is available in the full structured regimen.

References

DOI: 10.1093/ejendo/lvad066

We recommend open adrenalectomy is performed by an expert high-volume adrenal surgeon for unilateral adrenal masses with radiological findings suspicious of malignancy and signs of local invasion (⊕○○○).

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