Treatment of Behçet's Disease with Papulopustular or Acne-Like Mucocutaneous Lesions

This protocol covers Behçet's syndrome in patients presenting with papulopustular or acne-like mucocutaneous lesions — a recognised skin manifestation that spans a spectrum from mild localised eruptions to severe, chronic recurrent forms.

Papulopustular and acne-like lesions are a characteristic mucocutaneous feature of Behçet's syndrome. Their clinical behaviour and severity determine the treatment approach, with some cases following a persistent or particularly severe course.

For milder forms, topical measures — analogous to those used in acne vulgaris — are the starting point. When lesions become chronic, recurrent, or severe, systemic treatment options come into play.

The complete regimen — specific agents, escalation criteria, and sequencing — is available in the full structured protocol below.