Treatment of Behçet's Syndrome with Isolated Anterior Uveitis
When Behçet's syndrome presents with uveitis confined to the anterior segment — without posterior or systemic ocular involvement — the clinical picture calls for a scenario-specific treatment approach informed by individual prognostic factors.
Clinical Scenario
This protocol addresses Behçet's syndrome (BS) in the specific setting of isolated anterior uveitis. Certain patient characteristics — including younger age, male sex, and early disease onset — are recognised poor prognostic factors that shape treatment decisions in this presentation.
Treatment Approach
Management of isolated anterior uveitis in Behçet's syndrome begins with topical therapy, with systemic immunosuppressive treatment a further consideration for patients presenting with identified poor prognostic factors — the complete eligibility criteria, options, and sequence are detailed in the full protocol.
References
DOI: 10.1136/annrheumdis-2018-213225
- Isolated anterior uveitis in patients with BS may be treated with topical agents.
- Systemic immunosuppressives could be considered for those with poor prognostic factors such as young age, male sex and early disease onset.
- A systemic immunosuppressive such as azathioprine may be considered in such patients with the anticipation that it may have a protective effect.