Behçet's disease
ICD-10 M35.2 · ICD-11 4A62

Treatment of Behçet's Disease with Arthritis

Clinical Scenario

This protocol addresses Behçet's syndrome presenting with arthritis — a recognised musculoskeletal manifestation of the disease that requires structured clinical management to control joint inflammation and reduce recurrence.

Arthritis in Behçet's Syndrome

Arthritis is a significant feature of Behçet's syndrome and warrants a clear, stepwise treatment approach. Acute episodes are managed with initial therapy; when joint involvement becomes recurrent or persistent, the clinical pathway calls for escalation beyond the first step.

Treatment Approach

For recurrent or chronic arthritis in Behçet's syndrome, established immunomodulatory options are available — the structured protocol defines which agents to consider and when.

Full agent selection, criteria, and clinical decision pathway are in the complete protocol below.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1136/annrheumdis-2018-213225

Colchicine should be the initial treatment in BS patients with acute arthritis.

Azathioprine, interferon-alpha or TNF-alpha inhibitors should be considered in recurrent and chronic cases.

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