Treatment of Behçet's Disease with Acute Deep Vein Thrombosis
Clinical Scenario
This protocol covers patients with Behçet's syndrome who develop acute deep vein thrombosis — a serious vascular complication that requires a specific, evidence-based therapeutic approach distinct from routine DVT management.
Treatment Approach
Management centres on glucocorticoids combined with immunosuppressive therapy. The choice of immunosuppressive agent depends on the extent and distribution of the thrombosis — the full selection criteria and treatment algorithm are in the complete protocol.
References
DOI: 10.1136/annrheumdis-2018-213225
For the management of acute deep vein thrombosis in BS, glucocorticoids and immunosuppressives such as azathioprine, cyclophosphamide or cyclosporine-A are recommended.
Cyclophosphamide may be reserved for patients with extensive thrombosis of larger veins such as vena cava due to its potential adverse events.
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