Treatment of Locally Advanced Basal Cell Carcinoma with an Inoperable Tumor 10 mm or Larger

Clinical Scenario

This protocol applies to patients with locally advanced basal cell carcinoma (BCC) of the skin who have at least one tumor measuring 10 mm or more in diameter that is inoperable or considered inappropriate for surgery.

Patient Population

Eligibility requires at least one lesion 10 mm or larger in diameter judged inoperable or inappropriate for surgery in the opinion of a specialist in Mohs micrographic surgery, head and neck surgery, or plastic surgery.

Treatment Approach — Partial Overview

The criterion standard of therapy for locally advanced BCC involves surgical and radiation-based interventions. Full regimen details, sequencing, and clinical decision criteria are available in the complete protocol…

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1016/j.jaad.2017.10.006

Patients had at least 1 tumor 10 mm or larger in diameter that was considered inoperable or inappropriate for surgery in the opinion of a specialist in MMS, head and neck surgery, or plastic surgery.

Although surgery and radiation therapy remain the criterion standard of therapy, curative treatment may be associated with substantial morbidity.

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