Balanoposthitis in Uncircumcised Men Aged 40 or Older When First-Line Treatment Fails to Resolve Penile Lesions

Clinical Scenario

Zoon's (plasma cell) balanitis is a condition of the uncircumcised penis in patients aged 40 years or older. This protocol addresses cases where penile lesions have persisted despite first-line management.

First-Line Treatment — Insufficient Response

Initial management — including hygiene measures, treatment of underlying dermatoses, circumcision, topical corticosteroid preparations (such as clobetasone butyrate combinations), antibacterial creams (such as mupirocin), and topical calcineurin inhibitors (such as pimecrolimus) — has not achieved resolution of penile lesions.

Next Step

For persistent individual lesions following failure of first-line therapy, a targeted procedural intervention is available. The complete structured regimen, including evidence grading, is accessible via the link below.

Instant Access to Structured Evidence-Based Regimens
References
DOI: 10.1111/jdv.18954 View source ↗