Bacterial endophthalmitis is a serious intraocular infection requiring prompt, structured intervention. The choice and sequence of treatment depend on case severity and clinical presentation.
Management can involve a surgical approach — specifically, pars plana vitrectomy — alongside intravitreal antibiotic therapy, with fluoroquinolones used in combination in selected severe cases. The full regimen, selection criteria, and sequencing are detailed in the structured protocol.
Vitrectomy has been shown to improve visual outcome in severe postoperative EVS-eligible cases.
However, most reports agree that vitrectomy should be performed without delay in severe cases of endophthalmitis, especially those involving intraocular foreign bodies.
Despite this, fluoroquinolones in particular are currently used by many clinicians in combination with intravitreal antibiotics in management of some severe endophthalmitis cases.
DOI: 10.1128/CMR.15.1.111-124.2002
View source ↗