Autosomal dominant tubulointerstitial kidney disease
ICD-10 Q61.5; Q61.8 ICD-11 GB82

Treatment of Autosomal Dominant Tubulointerstitial Kidney Disease Progressing to Kidney Failure

Autosomal dominant tubulointerstitial kidney disease (ADTKD) is a hereditary condition that causes progressive deterioration of kidney function. When the disease advances to kidney failure, the clinical approach shifts to addressing end-stage renal function with a definitive intervention.

Treatment Approach
For ADTKD that has progressed to kidney failure, the evidence-based protocol involves a transplant-based intervention — with important implications specific to how ADTKD behaves in this setting.

The complete clinical pathway, eligibility considerations, and supporting evidence are in the full protocol.

Instant Access to Structured Evidence-Based Regimens

References

Kidney transplantation is the treatment of choice for kidney failure caused by ADTKD, as the disease does not recur in the graft.

DOI: 10.1038/ki.2015.28

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