علاج التهاب الدماغ الفيروسي في التهاب الدماغ بفيروس الهربس البسيط

References

DOI: 10.1086/589747

• Herpes simplex virus: acyclovir is recommended (A-I).
• Acyclovir is the treatment of choice for patients with herpes simplex encephalitis, but morbidity and mortality remain high (mortality at 18 months after treatment, 28%).
• A negative CSF PCR result at the end of therapy was associated with a better outcome, suggesting that another CSF specimen should be subjected to PCR for herpes simplex virus at the end of therapy in patients who have not had the appropriate clinical response; if the result is positive, antiviral therapy should be continued.