علاج سرطان المهبل في المرحلة الأولى (T1N0M0) لدى البالغين: آفة صغيرة حتى 2 سم

References

DOI: 10.1016/j.radonc.2023.109662

As complete tumour removal with free margins is the goal of any curative surgery for vaginal cancer, the surgical route should be pursued only for small size lesions (maximum size up to 2 cm) stage I (T1N0M0) disease, that are not close to urethra or rectum, so that they would require additional urological and/ or GI resections.

The surgical treatment consists of (partial) colpectomy and lymph node assessment depending on the location of the primary lesion [IV, A].

Primary chemoradiotherapy includes the combination of external beam radiotherapy (EBRT), brachytherapy and cisplatin-based chemotherapy as the recommended regimen.

In selected patients with tumours confined to the vaginal wall and a maximum size up to 2 cm and limited thickness (that can be appropriately covered by intracavitary technique alone, i.e. < 7 mm thick), brachytherapy alone can be considered, after comprehensive surgical lymph node staging.

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