علاج تمدد الأبهر الصدري غير المنفجر: التحكم في ضغط الدم وتعديل عوامل خطر القلب والأوعية الدموية

References

DOI: 10.1161/CIR.0000000000001106

• In patients with TAA and an average systolic BP (SBP) of ≥130 mm Hg or an average diastolic BP (DBP) of ≥80 mm Hg, the use of antihypertensive medications is recommended to reduce risk of cardiovascular events.
• In patients with TAA, regardless of cause and in the absence of contraindications, use of beta blockers to achieve target BP goals is reasonable.
• In patients with TAA, regardless of etiology and in the absence of contraindications, ARB therapy is a reasonable adjunct to beta-blocker therapy to achieve target BP goals.
• In patients with TAA and imaging or clinical evidence of atherosclerosis, statin therapy at moderate or high intensity is reasonable.
• In patients with TAA who smoke cigarettes, smoking cessation efforts are recommended.
• In patients with atherosclerotic TAA and concomitant aortic atheroma or PAU, the use of low-dose aspirin is reasonable, unless contraindicated.
• Uncontrolled hypertension increases the risk for aortic dissection, so achieving a SBP goal of ≤130 mm Hg and a DBP goal of ≤80 mm Hg, with the use of antihypertensive therapy in those with hypertension and TAA, is advised.