ما هو العلاج الخط الأول لألم العصب الثلاثي التوائم؟

References

• Carbamazepine - therapeutic range is normally between 800mg – 1200mg total daily dose split over 4 separated doses; modified release and liquid forms are also available.
• Recommend HLA-B*1502 allele testing in individuals of Han Chinese or Thai origin (risk of Stevens-Johnson syndrome in presence of HLA-B*1502 allele).
• Oxcarbazepine – alternative should there be medication interaction issues with carbamazepine.
• Therapeutic range is normally between 1200mg – 1800mg total daily dose split over 4 separated doses.
• However, once a remission period is noted i.e. no pain for at least 4 weeks, then the medication can be slowly tapered down and stopped.