علاج التهاب الأوعية الخثاري الطمسي مع العرج المتقطع في الأطراف

References

• DOI: 10.1155/2013/156905
• Other drugs that have been proven beneficial in TAO patients with intermittent claudication are naftidrofuryl (Praxilene), levocarnitine, arginine, buflomedil, ketanserin, niacin, and lovastatin.
• Though usage of pentoxyfylline may increase the pain-free walking distance in many, the long-term benefit and improvement in quality of life is limited.
• A dose of verapamil up to 480 mg/day can be given as an adjuvant therapy to patients.
• A dihydropyridine calcium channel blocker, such as amlodipine or nifedipine, seems to be effective if vasospasm is present.
• In a study by Bagger et al. increasing doses of verapamil was used in 44 patient of TAO; it was seen that there was an increased mean pain-free walking distance by 29% from 44.9 to 57.8 meters.
• Patient have to be informed beforehand and possibly starting with a lower dose, such as 50 mg once a day, then after approximately 1 week increasing to 50 mg twice a day and then increasing to the recommended dosage of 100 mg twice a day may alleviate most of these headaches.