ورم الخلايا الجرثومية للخصية مع نقائل دماغية موجودة عند التشخيص الأولي

References

1. Brain metastases occur in the context of initial metastatic disease, systemic relapse and rarely as an isolated site of relapse.
2. Chemotherapy as initial treatment proved effective in a first-line setting (potentially even as dose-intensified therapy upfront) with data also supporting the use of multimodal treatment particularly in relapsed disease.
3. Consolidation RT, even with total response after chemotherapy, should therefore be used in patients with brain metastases at relapse, but must be carefully discussed in a first-line setting.
4. Nowadays, stereotactic treatments offer superior outcomes both in terms of efficacy and side-effect profile.