علاج الصداع التوتري في الصداع التوتري المزمن (≥15 يومًا من الصداع في الشهر)

References

DOI: 10.1111/j.1468-1331.2010.03070.x

• Headache occurring on ‡15 days per month on average for >3 months (‡180 days per year) and fulfilling criteria B–D.
• Prophylactic pharmacotherapy should be considered in patients with chronic TTH, and it can be considered in patients with very frequent episodic TTH.
• The tricyclic antidepressant clomipramine 75–150 mg daily and the tetracyclic antidepressants maprotiline 75 mg daily and mianserin 30–60 mg daily have been reported more effective than placebo.
• Mirtazapine or venlafaxine are probably effective, whilst the older tricyclic and tetracyclic antidepressants, clomipramine, maprotiline and mianserin, may be effective.