علاج الساركوما الزليلية في البالغين (العمر 18 عامًا أو أكبر)

References

• Five-year survival rates in adults with SS have plateaued since the 1980s with no advances in treatment efficacy.
• For localized STS, treatment guidelines recommend surgical resection with wide excision with negative margins where possible, combined with radiotherapy (neoadjuvant or adjuvant) for intermediate-high-grade (grades 2-3), deep, >5 cm lesions.
• While the ESMO guidelines recommend three cycles of neoadjuvant full-dose anthracycline plus ifosfamide chemotherapy, due to noninferior OS compared with five cycles, treatment recommendations should be made on an individual basis in patients affected by more rare STS histological types.

DOI: 10.1016/j.esmoop.2023.101618