علاج الذئبة الحمامية الجلدية تحت الحادة مع الآفات الجلدية الموضعية

References

• Topical corticosteroids are the mainstay in the treatment of localized CLE being effective in all subtypes (Figure 1), but only few controlled studies have been published proving their efficacy.
• Since a long time, antimalarials are considered the first-line systemic treatment in all subtypes of CLE; however, only two randomized, double-blind studies in CLE or SLE with skin lesions were — to our knowledge — performed until now.
• We recommend to apply HCQ in a maximum daily dosage of 5 mg/kg real body weight or CQ in a maximum daily dosage of 2.3 mg/kg real body weight.
• A combination of HCQ with CQ must be avoided due to the risk of irreversible retinopathy.