العلاج الخطي الأول لسرطان المعدة المتقدم أو النقيلي: سلبي HER2، غير عالي MSI، درجة CPS لـ PD-L1 أقل من 5

References

DOI: 10.1016/j.annonc.2022.07.004

• Standard first-line ChT for gastric cancer is a platinum–fluoropyrimidine doublet.
• First-line ChT with a platinum and fluoropyrimidine is recommended. Oxaliplatin is preferred, especially for older patients [I, A].
• Recommended fluoropyrimidines are intravenous 5-FU, oral capecitabine or oral S-1.
• Irinotecan–5-FU can be considered an alternative option for patients who do not tolerate platinum compounds [II, B].