ما هو علاج الخط الأول لمتلازمة الشخص المتصلب؟

References

DOI: 10.1212/NXI.0000000000200109

• Collectively, the first choice of all antispasmodics is oral baclofen, combined with gabapentin and low doses of diazepam; the other aforementioned agents are reasonable alternates if well tolerated.
• These are the first-line therapies because they improve GABAergic inhibitory neurotransmission, suppress cortical hyperexcitability, or increase CNS GABA exerting a positive effect on impaired reciprocal inhibition and improving the 4 fundamental SPS symptoms mentioned earlier.