التهاب الصفاق البكتيري العفوي المكتسب من المجتمع لدى البالغين الذين لا يستجيبون للعلاج الأولي بالمضادات الحيوية

DOI: 10.1002/hep.31884

1. The diagnosis of SBP/SBE is established with a fluid polymorphonuclear (PMN) leukocyte count >250/mm³.
2. First-line empirical antibiotic therapy for community-acquired SBP/SBE is IV third-generation cephalosporin.
3. A negative response is defined by a decrease in PMN count <25% from baseline and should lead to broadening the antibiotic spectrum and investigating secondary peritonitis (abdominal imaging studies).
4. A decrease in fluid PMN <25% from baseline indicates lack of response and should lead to broadening of antibiotic coverage and further evaluation to rule out secondary bacterial peritonitis.