ما هو علاج الخط الأول لداء الشيغيلا؟

References

DOI: 10.1080/20469047.2017.1409454

• Current guidelines for treating shigella were published by WHO in 2005 and they recommend ciprofloxacin as the first-line treatment (Table 1).
• Shigella Dysenteriae Type 1 listed the fluoroquinolone ciprofloxacin (15 mg/kg orally twice daily for 3 days) as first-line treatment for shigellosis in children, and (more expensive and less available) pivmecillinam (amdinocillin pivoxil) and (parenteral) ceftriaxone were listed as second-line therapy when local strains were known to be resistant to ciprofloxacin.
• With effective antibiotic therapy, clinical improvement occurs within 48 h, resulting in a decreased risk of serious complications and death, shorter duration of symptoms, and the elimination of shigella from the stool.