علاج قصور الغدة الدرقية الثانوي في المرضى فوق 60 عامًا أو مع مرض القلب الإقفاري المعروف أو المشتبه به

References

1. Patients older than 60 years or with known or suspected ischemic heart disease should start at a lower dosage of levothyroxine (12.5 to 50 mcg per day).
2. For older patients or those with coronary artery disease, levothyroxine therapy should be started at 25 to 50 mcg per day, with titration of 25 mcg every three to four weeks until a target dosage is achieved to decrease the potential for adverse effects from thyroid excess (e.g., atrial fibrillation, dysrhythmia, angina, osteoporosis).
3. Starting as low as 12.5 mcg per day in patients at higher risk (e.g., advanced age, heart disease) should be considered.