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References

• Symptom relief and normalized thyroid-stimulating hormone levels are achieved with levothyroxine replacement therapy, started at 1.5 to 1.8 mcg per kg per day.
• Levothyroxine should be taken once per day, 30 to 60 minutes before eating, and four hours before or after drugs that may impede absorption (Table 5).
• In patients who are not pregnant, TSH should be monitored every six to eight weeks until within normal range, then every six to 12 months, barring a change in clinical status.