علاج التهاب الغضروف الانتكاسي في مرض المفاصل الالتهابي

References

Joint involvement is very frequent (52 to 85%). It most often presents as poly- or oligoarthritis or acute or sub-acute arthralgia which may be migratory.

If methotrexate fails, a second-line immunosuppressant (including azathioprine, mycophenolate mofetil and leflunomide) and/or targeted therapy (preferably anti-TNF or IL-6 receptor inhibitor) may be used. The use of cyclophosphamide, a potent immunosuppressant, is not indicated in joint disease due to a poor benefit–risk ratio.

DOI: 10.1016/j.revmed.2023.05.005