علاج داء النوكارديا الرئوي في حالات الانتشار أو المرض الشديد

DOI: 10.1093/cid/ciae643

In contrast, patients with severe nocardiosis are typically hospitalized and have a more rapid course from onset to diagnosis.

This is particularly crucial in severe forms of nocardiosis (eg, disseminated or progressive pulmonary infection), where 2 or 3 different agents are typically initiated empirically.

Once Nocardia susceptibility is determined, antibiotic therapy can be further tailored.

If combination therapy is started empirically, treatment can be narrowed to monotherapy, particularly if there are signs of clinical improvement.

Patients with pulmonary or CNS disease should undergo follow-up chest or brain imaging, respectively, to evaluate for response to treatment.