علاج داء النوكارديا الرئوي الخفيف غير المنتشر في المرضى الأسوياء مناعياً المصابين بأمراض الرئة المزمنة

References

DOI: 10.1093/cid/ciae643

• Although no validated grading system for Nocardia severity exists, patients with mild nocardiosis are often managed in the outpatient setting, have a chronic course leading to diagnosis, and have nondisseminated infection.
• Additionally, select immunocompetent patients with mild pulmonary nocardiosis (typically those with chronic pulmonary disease) can be closely monitored until susceptibility results are available.
• Conversely, those with mild infection can start with a single antibiotic that is highly likely to be an active agent.
• If combination therapy is started empirically, treatment can be narrowed to monotherapy, particularly if there are signs of clinical improvement.
• Patients with pulmonary or CNS disease should undergo follow-up chest or brain imaging, respectively, to evaluate for response to treatment.