علاج التهاب الأقنية الصفراوية التصلبي الأولي مع التضيق السائد والحكة والتهاب الأقنية الصفراوية

References

DOI: 10.1038/ajg.2015.112

• ERCP with balloon dilatation is recommended for PSC patients with dominant stricture and pruritus, and/or cholangitis, to relieve symptoms.
• PSC patients undergoing ERCP should have antibiotic prophylaxis to prevent post-ERCP cholangitis.
• Routine stenting after dilation of a dominant stricture is not required, whereas short-term stenting may be required in patients with severe stricture.
• Preoperative antibiotics followed by a 3- to 5-day course post ERCP have been advised, using quinolones or cephalosporins, although no prospective studies have been performed to determine the best antibiotic choices.
• In patients with deterioration and a dominant stricture perform ERCP with peri-procedure antibiotics and consider balloon dilation, with stent if needed.