علاج الـ ALCL الجلدي الأولي المصحوب بآفات جلدية متعددة البؤر

References

1. Patients presenting with multifocal skin lesions can best be treated with low-dose MTX, as in LyP [IV, A], or with RT [IV, A] in the case of only a few lesions.
2. In the case of cosmetically disturbing lesions (e.g. scarring or many papulonodules), low-dose oral MTX (5–20 mg/week) and PUVA are the most effective therapies for reducing the number of skin lesions [IV, A].
3. For patients with multifocal or relapsing skin lesions, a radiation dose of 8 Gy (2 × 4 Gy) was suggested.