إدارة متلازمة ما قبل الحيض المقاومة والآثار الجانبية البروجستينية المستمرة

References

• GnRH analogues with add-back HRT are recommended for resistant PMS or persistent progestogenic side-effects.
• When treating women with PMS with GnRHa therapy, treatment should only be continued for 6 months when used alone.
• Treatment should be combined with HRT to reduce bone density loss.
• A recent meta-analysis of GnRH analogues has confirmed their efficacy compared with placebo.