الألم العصبي التالي للهربس غير المُسيطر عليه بالعلاج من الخط الأول

References

• In contrast, capsaicin 8% and opioids are considered second-line medications.
• Capsaicin 8% patches are currently considered a second-line medication for post-herpetic neuralgia.
• In a meta-analysis of four randomized trials involving 1,272 PHN patients, a single application of an 8% capsaicin patch to the skin was found to be significantly more effective in treating neuropathic pain than 0.014% topical capsaicin.
• In PHN, opioid drugs are mainly administered in oral form, although there are studies and case reports showing that in certain patients administering them in transdermal form can provide effective pain control.
• In one study, transdermal oxycodone proved effective in a group of severe paresthesia sufferers and had fewer gastrointestinal side-effects than the oral form of the drug.