العلاج من الخط الثاني للفقاع الورقي الخفيف عند عدم تحقيق السيطرة على المرض بالعلاج الخط الأول

References

DOI: 10.1111/jdv.16752

• PF with involved body surface area (BSA) <5%
• PDAI score ≤ 15.
• Rituximab: two infusions of 1g two weeks apart, alone, or associated with topical corticosteroids or oral prednisone 0.5 mg/kg/day, in patients previously treated with dapsone or topical corticosteroids
• Systemic corticosteroids: prednisone 0.5–1.0 mg/kg/day with or without azathioprine (1 to 2.5 mg/kg/d), or mycophenolate mofetil 2g/day or mycophenolate sodium 1440 mg/d – if rituximab is not available or contraindicated