سرطان تجويف الفم: العلاج في الخط التالي عندما لا يحقق الاستئصال الجراحي هوامش خالية من الورم بشكل كامل

References

• Postoperative radio- or radiochemotherapy shall be given in cases of advanced T category (T3/T4), scarce or positive resection margins, perineural invasion, vascular invasion, and/or lymph node involvement.
• Postoperative radiotherapy shall be conventionally fractionated and delivered at 54–60 Gy in 27–30 fractions over 5.5–6 weeks for average risk tumors and 66 Gy in 33 fractions over 6.5 weeks for tumors at increased risk of recurrence.
• Postoperative radiotherapy should be started as early as possible and completed within a maximum period of 11 weeks after surgery.
• If radiotherapy is indicated, patients with increased histopathological risk criteria for tumor recurrence (resection margin <5 mm and/or extracapsular tumor growth) should receive adjuvant treatment in the form of radiochemotherapy with cisplatin after tumor resection.