متلازمة الكلية النيفروتية لدى الأطفال: ماذا تفعل عندما لا يحقق العلاج الأولي بالكورتيكوستيرويدات الهدأة الكاملة

References

• The initial approach to relapse should include oral prednisone or prednisolone as a single daily dose of 60 mg/m² per day or 2 mg/kg per day (maximum 60 mg/d) until the child remits completely for ≥3 days.
• After achieving complete remission in patients with steroid-sensitive nephrotic syndrome treated for relapse, reduce oral prednisone/prednisolone to 40 mg/m² or 1.5 mg/kg (maximum 40 mg) on alternate days for 4 weeks.
• Complete remission: First morning urine or 24-h uPCR ≤200 mg/g (0.2 g/g or 20 mg/mmol or negative or trace dipstick or <100 mg/m² per day) on three or more consecutive days.