علاج التهاب اللفافة الناخر في حالة توثيق عدوى المكورات العقدية من المجموعة أ (Streptococcus pyogenes)

References

DOI: 10.1093/cid/ciu296

• Penicillin plus clindamycin is recommended for treatment of documented group A streptococcal necrotizing fasciitis (strong, low).
• Necrotizing fasciitis and/or streptococcal toxic shock syndrome caused by group A streptococci should be treated with both clindamycin and penicillin.
• Penicillin should be added because of potential resistance of group A streptococci to clindamycin.
• In the absence of definitive clinical trials, antimicrobial therapy should be administered until further debridement is no longer necessary, the patient has improved clinically, and fever has been absent for 48-72 hours.