علاج تضخم الغدة الدرقية العقدي المتعدد الحميد المصحوب بأعراض ضغطية

References

DOI: 10.1530/ETJ-23-0067

• Consider RAI as an alternative to surgery in benign normo-functioning multinodular goiter.
• When symptomatic and benign, thyroid nodules may, as an alternative to surgery, be eligible for RAI, especially in case of patients at surgical risk.
• RAI is most often given as a fixed activity, most often achieves euthyroidism, may cause hypothyroidism, and reduces nodule size by 30–50% in 12 months.
• In case of low RAI uptake and/or a large goiter, prestimulation with rhTSH has been demonstrated to augment thyroid volume reduction and improves pressure symptoms.
• Thyroid volume is typically reduced by 40% within 12 months and alleviates symptoms in most.