انتكاس مرض التغيرات الطفيفة بعد العلاج الأولي بالكورتيكوستيرويدات: إدارة الخطوة التالية

References

DOI: 10.1038/kisup.2012.18

• Infrequent relapses may be treated with glucocorticoids without incurring major side effects if the duration of therapy is limited.
• One regimen is to administer oral prednisone at a daily dose of 1 mg/kg (maximum dose of 80 mg/d) for 4 weeks or until remission is achieved, followed by 5-mg decrements every 3–5 days to discontinuation within 1–2 months.
• In 1 study, patients were treated with 20–30 mg of prednisolone for a minimum of 7 days or additionally with cyclophosphamide until proteinuria returned to a normal range, suggesting that the high doses of glucocorticoids, as with the initial treatment of MCD, may not be needed.