علاج الخط الأول بالمسكنات ومضادات الالتهاب غير الستيرويدية للشقيقة بدون هالة

References

DOI: 10.1177/2514183X1882337

• Analgesics like acetylsalicylic acid and non-steroidal anti-inflammatory drugs (NSAIDs) are effective in the treatment of migraine.
• Mild and moderate migraine attacks should be treated initially with these substances.
• The effectiveness has been best demonstrated for ASA and ibuprofen.
• Anti-emetics like metoclopramide or domperidone are effective in the treatment of nausea and vomiting during a migraine attack.
• Prokinetic and anti-emetic medications should generally not be combined with analgesics or triptans but used for targeted treatment of severe nausea or vomiting.
• In a randomized-controlled trial (RCT), no significant difference could be observed between the dosages 200 mg, 400 mg and 600 mg ibuprofen for the primary endpoint headache reduction 2 h after taking the medication.